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A Companion to Science Fiction Edited by David Seed A Companion to Narrative Theory Edited by James Phelan and Peter J. A Companion to Tragedy Edited by Rebecca Bushnell 33. A Companion to Old Norse-Icelandic Literature and Culture Edited by Rory McTurk 32. A Companion to the Eighteenth-Century Novel and Culture Edited by Paula R. A Companion to Twentieth-Century American Drama Edited by David Krasner 30. A Companion to the British and Irish Novel 1945–2000 Edited by Brian W. A Companion to Romance Edited by Corinne Saunders 28. A Companion to Digital Humanities Edited by Susan Schreibman, Ray Siemens, and John Unsworth 27. A Companion to American Fiction 1865–1914 Edited by Robert Paul Lamb and G.R. A Companion to American Fiction 1780–1865 Edited by Shirley Samuels 25. A Companion to the Literature and Culture of the American South Edited by Richard Gray and Owen Robinson 24. A Companion to Rhetoric and Rhetorical Criticism Edited by Walter Jost and Wendy Olmsted 23. A Companion to the Regional Literatures of America Edited by Charles L. A Companion to Shakespeare’s Works: Volumes I–IV Edited by Richard Dutton and Jean E. A Companion to the Victorian Novel Edited by Patrick Brantlinger and William B. A Companion to Victorian Poetry Edited by Richard Cronin, Alison Chapman, and Antony H. A Companion to Renaissance Drama Edited by Arthur F. A Companion to Early Modern Women’s Writing Edited by Anita Pacheco 14. A Companion to Restoration Drama Edited by Susan J. A Companion to Anglo-Saxon Literature and Culture Edited by Phillip Pulsiano and Elaine Treharne 12. A Companion to Twentieth-Century Poetry Edited by Neil Roberts 11. A Companion to Milton Edited by Thomas N. A Companion to English Renaissance Literature and Culture Edited by Michael Hattaway 9. A Companion to Literature from Milton to Blake Edited by David Womersley 8.

A Companion to Chaucer Edited by Peter Brown 7. A Feminist Companion to Shakespeare Edited by Dympna Callaghan 6. A Companion to the Gothic Edited by David Punter 5. A Companion to Shakespeare Edited by David Scott Kastan 4. A Companion to Victorian Literature and Culture Edited by Herbert F. A Companion to Romanticism Edited by Duncan Wu 2. Extensive volumes provide new perspectives and positions on contexts and on canonical and post-canonical texts, orientating the beginning student in new fields of study and providing the experienced undergraduate and new graduate with current and new directions, as pioneered and developed by leading scholars in the field.

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J Biomed Mater Res Part A: 107A: 92–103, 2019.S CIENCE F ICTION E D I T E D B Y D AV I D S E E Dīlackwell Companions to Literature and Culture This series offers comprehensive, newly written surveys of key periods and movements and certain major authors, in English literary culture and history. Biomimetic sponges implanted in a mouse model of volumetric muscle loss (VML) supported satellite, endothelial, and inflammatory cell infiltration but resulted in limited myofiber regeneration at 2 weeks post-injury. The myoblasts produced higher levels of myokines such as VEGF, IL-6, and IGF-1 and showed higher expression of myogenic markers such as MyoD and myogenin on the biomimetic sponges. The biomimetic sponges supported the infiltration and viability of C 2C 12 myoblasts over 5 days of culture. Morphological and mechanical evaluation of the sponges showed porous structure, water-retention capacity and a compressive modulus of 590–808 kPa. Collagen and LM-111 are crucial components of the muscle extracellular matrix and were chosen to impart bioactivity whereas gelatin and EDC were used to provide mechanical strength to the scaffold. To improve regeneration of skeletal muscle, we have developed biomimetic sponges composed of collagen, gelatin, and laminin (LM)-111 that were crosslinked with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC). Skeletal muscle is inept in regenerating after traumatic injuries due to significant loss of basal lamina and the resident satellite cells.

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